Corneal endothelial grid structure factor based on coefficient of variation of the cell sides lengths

Abstract

Description of the corneal endothelial cell grid is a valuable diagnostic pointer, used in Ophthalmology. Until now, two quality factors were used: hexagonality (H) and the relative standard deviation of the cell surface (CV). Both the factors do not take into account the length measure of the grid cells, which has been presented in an article on the sample images. The authors propose an additional factor, the average relative standard deviation of the cell sides lengths (CVSL), which takes the cells non-uniformity into account.