Taking a bite out of Wnts

Abstract

Proper control of intercellular communication through the Wnt signaling pathway is of critical importance for many aspects of biology, including head formation during vertebrate embryogenesis. A recent Cell paper describes the discovery of a novel protein, TIKI, which controls head size through a surprising new mechanism of Wnt antagonism. © 2012 IBCB, SIBS, CAS All rights reserved.