Meta-Analysis: The Effect of Anemia, Pre-Eclampsia and Parity on the Prevalence of Low-Birth-Weight Infants in Indonesia

Abstract

The incidence of LBW in Indonesia varies greatly from one region to another. Nationally based on the Indonesian health demographic survey, the incidence of LBW has increased to 6.2% in 2018. This study aims to determine the magnitude of anemia, pre-eclampsia and parity on the incidence of LBW. LBW in Indonesia. This study is a meta-analysis using PRISMA, obtained 22 journals containing case-control and cross-sectional journals from 1219 from two databases, namely PubMed and scholar, data presentation using forest plots obtained using the Rev.Man 5.3 application. The magnitude of the combined odds ratio (OR) shows that the effect of anemia on LBW is 3.25, anemia tends to have a large effect on the incidence of LBW with a value of 3.65, then the effect of pre-eclampsia on LBW is 2.70, pre-eclampsia tends to have a similar effect. large in the incidence of LBW with a value of 5.50 while the effect of parity on LBW is 1.45 parity tends to have a large effect on the incidence of LBW with a value of 1.30. In the three variables analyzed by meta-analysis, the greatest influence on the incidence of LBW is pre-eclampsia. There is an influence of anemia, pre-eclampsia and parity on the incidence of LBW, early detection of anemia should be carried out early and need to be evaluated after giving Fe. In pre-eclampsia, it is necessary to have an early examination during pregnancy visits, while at parity, it must be socialized and evaluated again for the family planning program. so that the incidence of LBW can be reduced. Keywords: anemia, pre-eclampsia, parity, LBW, meta-analysis