Glycosides from the aerial parts of patrinia villosa

Abstract

An investigation of the Korean medicinal plant Patrinia villosa (Thunb.) Juss. (Valerianaceae) led to the isolation of two new flavonoid glycosides, patrivilosides 1 (1) and 2 (2), a new iridoid glycoside, patrinovalero-sidate (3), and two new saponins, patrinovilosides A (4) and B (5), along with six known compounds including three flavonoid glycosides and three iridoid glycosides. The structures of the new compounds were elucidated based on analysis of their one dimensional (ID)- and 2D-NMR spectra along with their mass spectrometric data and the results of acid hydrolysis. © 2013 The Pharmaceutical Society of Japan.