Genetic determinants of circulating galectin-3 levels in patients with coronary artery disease

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Abstract

Background: Galectin-3 plays a crucial role in the regulation of inflammation. The aim of this study was to elucidate the association between LGALS3 genotypes, galectin-3 levels, and inflammatory marker levels in patients with coronary artery disease (CAD). Results: A total of 474 patients with CAD were enrolled. Significant correlations were discerned between galectin-3 levels and leukocyte counts, C-reactive protein, soluble intercellular adhesion molecule-1, and matrix metalloproteinase 9 levels (all p

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Liao, Y. H., Teng, M. S., Juang, J. M. J., Chiang, F. T., Er, L. K., Wu, S., & Ko, Y. L. (2020). Genetic determinants of circulating galectin-3 levels in patients with coronary artery disease. Molecular Genetics and Genomic Medicine, 8(9). https://doi.org/10.1002/mgg3.1370

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