Progress in Natural Product Chemistry by the Chiron and Related Approaches—Synthesis of Avermectin B1a

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Abstract

A strategy for the total synthesis of avermectin Blais presented based on aspects of the utilization of chirons derived from naturally-occurring starting materials, asymmetric synthesis, and computer-assisted stereochemical analysis. © 1987 IUPAC

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Hanessian, S., Ugolini, A., Hodges, P. J., Beaulieu, P., Dubé, D., & André, C. (1987). Progress in Natural Product Chemistry by the Chiron and Related Approaches—Synthesis of Avermectin B1a. Pure and Applied Chemistry, 59(3), 299–316. https://doi.org/10.1351/pac198759030299

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