Since the advent of high angular resolution diffusion imaging (HARDI) techniques in diffusion MRI great efforts have been taken in order to reconstruct complex white-matter structures, such as crossing, branching and kissing fibers. However, even highly sophisticated fiber tracking schemes, such as probabilistic tracking, suffer from the data's poor signal-to-noise (SNR) ratio. In this paper we present a novel regularization approach for q-ball fields, exploiting structural information within the data. We also propose a straightforward deterministic tracking algorithm, allowing delineation of even non-dominant pathways through crossing regions. Results from a phantom study with a biological phantom as well as a patient study, in which we reconstruct the pyramidal tract, emphasize the method's efficiency. © 2009 Springer Berlin Heidelberg.
CITATION STYLE
Ehricke, H. H., Otto, K. M., Kumar, V., & Klose, U. (2009). Diffusion mri tractography of crossing fibers by cone-beam odf regularization. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 5748 LNCS, pp. 412–421). https://doi.org/10.1007/978-3-642-03798-6_42
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