The effect of giving mannan extract from palm kernel cake to pathology and histopathology liver and intestine chicken which infected by Salmonella thypimurium

Abstract

Salmonella thypimurium is an enteric disease in poultry and still a major problem in the livestock industry and human health because it is zoonotic. Mannan Oligosaccharide was originated from palm kernel cake which expected to replace the role of antibiotics. The purpose of this study was to find out the effect of giving mannan extract to relative weight of liver and intestine, pathology and histopathology changes on liver and intestines from broiler chicken. This test was used ninety six broiler chicken of 1 day age Cobb strain infected orally with 105 CFU S. thypimurium on the third day. Levels of the mannan extract given were 0%, 0.1%, 0.2%, 0.3%, 0.4% and antibiotic as controls. The results showed that giving of mannan extract to relative weight of liver and intestine was not significant (P> 0.05). On the observation the effect of giving mannan extract to pathology and histopathology showed that it was not significant (P> 0.05) It is concluded that mannan extract is safe to use in livestock because it was not affected to the intestine and liver organ.