Background: Phase-contrast MRI (PC-MRI) has previously been used for the quantification of CSF and blood flow throughout the body. We propose a new method of semi-automated segmentation for the prepontine cistern based on anatomical and pulsatility information. Methods: Scans were conducted on 48 patients (69.83 ± 14.28 years) ranging in age from 32 to 88 years along with an additional 11 controls (51.91 ± 21.13 years) ranging in age from 22 to 72 years. The segmentation algorithm developed consists of four stages: anatomical, flow quantification for the aqueduct and prepontine cistern, and blood vessel detection. Results: Complete results are presented in Table 1, the 37 preoperative patients and controls had a prepontine cistern stroke volume of 464.32 ± 202.30 and 447.38 ± 75.49 respectively. Conclusion: Reliable quantification of volumetric CSF flow in complex cisternal spaces is possible using a methodology combining known anatomical features with the pulsatile nature of CSF flow. © 2012 Springer-Verlag/Wien.
CITATION STYLE
Hamilton, R., Dye, J., Frew, A., Baldwin, K., Hu, X., & Bergsneider, M. (2012). Quantification of pulsatile cerebrospinal fluid flow within the prepontine cistern. In Acta Neurochirurgica, Supplementum (Vol. 114, pp. 191–195). Springer-Verlag Wien. https://doi.org/10.1007/978-3-7091-0956-4_37
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