Role of reaction kinetics and mass transport in glucose sensing with nanopillar array electrodes

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Abstract

The use of nanopillar array electrodes (NAEs) for biosensor applications was explored using a combined experimental and simulation approach to characterize the role of reaction kinetics and mass transport in glucose detection with NAEs. Thin gold electrodes with arrays of vertically standing gold nanopillars were fabricated and their amperometric current responses were measured under bare and functionalized conditions. Results show that the sensing performances of both the bare and functionalized NAEs were affected not only by the presence and variation of the nanoscale structures on the electrodes but also by the reaction kinetics and mass transport of the analyte species involved. These results will shed new light for enhancing the performance of nanostructure based biosensors. © 2007 Anandan et al; licensee BioMed Central Ltd.

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Anandan, V., Yang, X., Kim, E., Rao, Y. L., & Zhang, G. (2007). Role of reaction kinetics and mass transport in glucose sensing with nanopillar array electrodes. Journal of Biological Engineering, 1. https://doi.org/10.1186/1754-1611-1-5

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