The Paterson-Kelly Syndrome

Abstract

An investigation of 55 cases of the Paterson-Kelly syndrome showed a high incidence of iron deficiency, achlorhydria, and subnormal vitamin-B12 absorption. It is suggested that this syndrome is associated with the genetically determined gastric atrophy found in patients with pernicious anaemia and that iron deficiency is a secondary feature. We are indebted to the staff of the Cardiff Royal Infirmary, who have allowed us to investigate patients under their care, and to Professor H. Scarborough for his helpful criticism. One of us (A. J.) is in receipt of a grant from the Endowment Fund of the United Cardiff Hospitals. © 1964, British Medical Journal Publishing Group. All rights reserved.