Analgesics and Opioids

Abstract

Analgesia may be enhanced with non-opioid and opioid analgesics, as well as coanalgesic agents.Non-opioid analgesics and short-acting opioids in chronic pain should be limited to infrequent, intermittent use for severe pain flares.Long-term risk for gastric and renal toxicity with analgesics is minimized with opioid analgesics.Medication abuse behavior occurs in 25–30% of patients with chronic pain treated with opioids.