Factors associated with dry eye symptoms in elderly Koreans: The Fifth Korea National Health and Nutrition Examination Survey 2010-2012

Abstract

Background: Dry eye disease is an aging-related ophthalmic disease that not only affects the daily activities but also causes deterioration in the quality of life. This study aimed to evaluate the factors associated with dry eye symptoms in elderly Koreans. Methods: We investigated 4,185 subjects (men=1,787 and women=2,398) aged ≥65 years from the fifth Korea National Health and Nutrition Examination Survey 2010-2012. Data were analyzed using multiple logistic regressions to identify the relationships between dry eye symptoms and other factors. Results: The prevalence of dry eye symptoms was 17.9%. After adjustment for confounding factors, dry eye symptoms were significantly associated with female sex (adjusted odds ratio [aOR], 1.806; 95% confidence interval [CI], 1.410-2.313), a history of cataract (aOR, 1.683; 95% CI, 1.255-2.255), suicidal ideation (aOR, 1.414; 95% CI, 1.070-1.870), hypercholesterolemia (aOR, 1.289; 95% CI, 1.025-1.621), age ≥80 years (aOR, 0.538; 95% CI, 0.337-0.859), and sleep duration ≥9 h/d (aOR, 0.524; 95% CI, 0.330-0.834). Conclusion: Among elderly Koreans, female sex, a history of cataract, suicidal ideation, and hypercholesterolemia may be the risk factors for dry eye symptoms, whereas sleep duration ≥9 h/d can be a protective factor against dry eye symptoms.