Decellularized bone matrix scaffold for bone regeneration

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Abstract

Decellularized bone matrix is gaining a lot of attention as implantable biomaterials and/or biological scaffolds for bone tissue repair, and shows good clinical performance. This chapter describes the processing techniques and characterization protocols of decellularized bone. For the applications of the decellularized bone scaffold in promoting bone repair and regeneration, we discuss some of the current advances, and highlight the advantages and disadvantages of these scaffolds. Fabrication and application of the hydrogel derived from decellularized bone for bone tissue engineering are also presented.

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Chen, G., & Lv, Y. (2018). Decellularized bone matrix scaffold for bone regeneration. In Methods in Molecular Biology (Vol. 1577, pp. 239–254). Humana Press Inc. https://doi.org/10.1007/7651_2017_50

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