Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) is a histological method used for various molecules including gangliosides. The method is based on mass spectrometry, and thus target molecules with small structural differences are directly and independently detected. Here we describe a general procedure and related key notes for analyzing major brain gangliosides by MALDI-IMS.
CITATION STYLE
Sugiyama, E., & Setou, M. (2018). Visualization of brain gangliosides using MALDI imaging mass spectrometry. In Methods in Molecular Biology (Vol. 1804, pp. 223–229). Humana Press Inc. https://doi.org/10.1007/978-1-4939-8552-4_10
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