In this issue of Cell Stem Cell, Min et al. (2008) identify Egr1 as a novel hematopoietic stem cell (HSC) transcription factor that regulates proliferation and mobilization of these cells. An improved understanding of Egr1 targets may lead to better strategies to expand populations of HSCs ex vivo for therapeutic applications. © 2008 Elsevier Inc. All rights reserved.
Magnusson, M., & Mikkola, H. K. A. (2008, April 10). Hematopoietic Stem Cells in Transit- Where’s the Niche? Cell Stem Cell. https://doi.org/10.1016/j.stem.2008.03.017