Increased serum myeloid-related protein 8/14 level is associated with atherosclerosis in type 2 diabetic patients

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Abstract

Myeloid-related protein 8/14 (MRP8/14) is a stable heterodimer formed by two different calcium-binding proteins (MRP8 and MRP14). Studies have identified that MRP8/14 regulates vascular inflammation and serves as a novel marker of acute coronary syndrome. In this study, we evaluated the correlation between serum levels of MRP8/14, hsCRP, endogenous secretory receptor for advanced glycation end-products (esRAGE) and the occurrence of coronary artery disease (CAD), or carotid intima-media thickness (IMT) when CAD was not yet developed in diabetic patients.

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Peng, W. H., Jian, W. X., Li, H. L., Hou, L., Wei, Y. D., Li, W. M., & Xu, Y. W. (2011). Increased serum myeloid-related protein 8/14 level is associated with atherosclerosis in type 2 diabetic patients. Cardiovascular Diabetology, 10. https://doi.org/10.1186/1475-2840-10-41

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