Purpose: To evaluate the role of intravenous methyl prednisolone in patients with solitary cysticercus granuloma with new-onset seizures. Methods: In this open-label, randomized, prospective, follow-up study, 52 patients with new-onset seizures and a single enhancing CT lesion of cysticercus were randomly divided in two groups to receive either intravenous methyl prednisolone for 5 days along with antiepileptic drug (n = 25) or antiepileptic drug monotherapy (n = 27) alone. The patients were followed up for at least for 9 months. Repeat CT scans were performed after 2 months. Results: After 2 months, lesion disappeared in 60% patients of intravenous methyl prednisolone group and 18.5% patients receiving only antiepileptic drug (p = 0.001). As far as seizure recurrence was concerned, a lower number (16% versus 33%) of intravenous methyl prednisolone treated patient had recurrence, the difference was insignificant. Conclusion: Intravenous methyl prednisolone therapy helps in early resolution of solitary cysticercus granuloma. © 2006 British Epilepsy Association.
Prakash, S., Garg, R. K., Kar, A. M., Shukla, R., Agarwal, A., Verma, R., & Singh, M. K. (2006). Intravenous methyl prednisolone in patients with solitary cysticercus granuloma: A random evaluation. Seizure, 15(5), 328–332. https://doi.org/10.1016/j.seizure.2006.03.003