Low-grade inflammation may moderate the effect of behavioral treatment for chronic pain in adults

14Citations
Citations of this article
56Readers
Mendeley users who have this article in their library.

Abstract

The purpose of the present pilot study was to explore the moderating role of basal inflammation on the effects of behavioral pain treatment in 41 patients with long-standing pain. Baseline pro-inflammatory status moderated behavioral treatment outcomes: higher pre-treatment levels of Tumor Necrosis Factor (TNF)-α and Interleukin (IL)-6 were related to less improvement in pain intensity, psychological inflexibility and in mental health-related quality of life. The treatment outcomes improved in the subgroup that had low levels of pro-inflammatory cytokines at baseline, while the subjects with higher pro-inflammatory status did not. Altogether, results indicate that low-grade inflammation may influence the behavioral treatment outcomes and provide a possible explanation of the heterogeneity in treatment response.

Cite

CITATION STYLE

APA

Lasselin, J., Kemani, M. K., Kanstrup, M., Olsson, G. L., Axelsson, J., Andreasson, A., … Wicksell, R. K. (2016). Low-grade inflammation may moderate the effect of behavioral treatment for chronic pain in adults. Journal of Behavioral Medicine, 39(5), 916–924. https://doi.org/10.1007/s10865-016-9769-z

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free