Opi1p, a transcription regulator of phospholipid metabolism in budding yeast, is retained in the endoplasmic reticulum by association with Scs2p. New research shows that binding of phosphatidic acid to Opi1p is a prerequisite for this targeting.
Daum, G. (2004, September 7). Membrane targeting: Glued by a lipid to the ER. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2004.08.045