Memory NK Cells Take Out the (Mitochondrial) Garbage

Abstract

The molecular mechanisms important to generate innate natural killer cell "memory" are poorly understood. In this issue of Immunity, O'Sullivan et al. (2015) demonstrate that mitophagy plays a critical role in natural killer cell memory formation following viral infection. The molecular mechanisms important to generate innate natural killer cell "memory" are poorly understood. Sun and colleagues demonstrate that mitophagy plays a critical role in natural killer cell memory formation following viral infection.