Munc13-4 Is Essential for Cytolytic Granules Fusion and Is Mutated in a Form of Familial Hemophagocytic Lymphohistiocytosis (FHL3) cytotoxic granules at the immunological synapse. HMunc13-4 is therefore essential for the priming step of cytolytic granules secretion preceding vesicle membrane fusion

rô me Feldmann, J., Callebaut, I., Raposo, G., phanie Certain, S., Bacq, D., cile Dumont, C., … Tamary, H. (2003). Munc13-4 Is Essential for Cytolytic Granules Fusion and Is Mutated in a Form of Familial Hemophagocytic Lymphohistiocytosis (FHL3) cytotoxic granules at the immunological synapse. HMunc13-4 is therefore essential for the priming step of cytolytic granules secretion preceding vesicle membrane fusion. Cell (Vol. 115, pp. 461–473). Retrieved from www.ncbi.nlm.nih.gov/mapview