Inflammation contributes to cardiovascular complications in type 2 diabetes, which are often characterized by microvascular alterations. We investigated whether myeloid-related protein 8/14 complex (MRP8/14) secreted by transmigrating monocytes and granulocytes may represent a biomarker for microvascular alterations in patients with type 2 diabetes and nephropathy.
Burkhardt, K., Schwarz, S., Pan, C., Stelter, F., Kotliar, K., Von Eynatten, M., … Baumann, M. (2009). Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy. Cardiovascular Diabetology, 8. https://doi.org/10.1186/1475-2840-8-10