Newly synthesized water soluble Cholinium-Purpurin photosensitizers and their stabilized gold nanoparticles as promising anticancer agents

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Abstract

For possible future use in Photodynamic Therapy (PDT) and/or Photothermal Therapy (PTT) of cancer and screening of cancer cells a new type of ionic liquid photosensitizer -Cholinium-Purpurin-18 (Chol-Pu-18) - was synthesized and small gold (Au) nanoparticles, stabilized by this photosensitizer were prepared without adding any particular reducing agents and CTAB. UV-Vis spectroscopy and Transmission Electron Microscopy (TEM) were used for characterization of the nanoparticles and FAB-MS and NMR of the ionic liquid choline hydroxide, purpurin carboxylate and their ionic liquid type of photosensitizer were obtained.

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Demberelnyamba, D., Ariunaa, M., & Shim, Y. K. (2008). Newly synthesized water soluble Cholinium-Purpurin photosensitizers and their stabilized gold nanoparticles as promising anticancer agents. International Journal of Molecular Sciences, 9(5), 864–871. https://doi.org/10.3390/ijms9050864

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