Objective: Determine the proportion of patients with chronic critical limb ischemia (CLI) who failed to adhere to Trans-Atlantic Inter-Society Consensus II guidelines of medical therapy and to quantify the effect of baseline suboptimal medical management on amputation-free survival (AFS). Methods: The patients were identified from a prospectively maintained database of consecutive patients presenting with CLI to the Vascular Surgery service at a single hospital. The primary outcome variable was AFS. The effects of baseline demographics, comorbid medical conditions, ambulatory status, optimal medical management, and Rutherford classification were assessed. Significant univariate predictors (P
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Chung, J., Timaran, D. A., Modrall, J. G., Ahn, C., Timaran, C. H., Kirkwood, M. L., … Valentine, R. J. (2013). Optimal medical therapy predicts amputation-free survival in chronic critical limb ischemia. In Journal of Vascular Surgery (Vol. 58, pp. 972–980). https://doi.org/10.1016/j.jvs.2013.03.050
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