Percutaneous implantation of a ventricular partitioning device for treatment of ischemic heart failure: Initial experience of a center

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Abstract

The Parachute is a novel left ventricular (LV) partitioning device that is deployed percutaneously in the left ventricle in patients with anteroapical regional wall motion abnormalities, dilated LV and systolic dysfunction after anterior myocardial infarction (Ml). The implantable device is a partitioning membrane that isolates the dysfunctional region of the ventricle and decreases chamber volume. Data from the first-in-human clinical trial - the Percutaneous Ventricular Restoration in Chronic Heart Failure (PARACHUTE) trial- has shown that this new device is associated with significant and sustained LV volume reduction and improvement in LV hemodynamics and functional capacity in the 12 months after implantation, with a relatively low rate of clinical events, indicating that it may have a beneficial effect in the treatment of ischemic heart failure. We aim to describe our initial experience with implantation of the Parachute LV partitioning device and its short-term safety, defined as the successful delivery and deployment of the device. © 2012 Sociedade Portuguesa de Cardiologia Published by Elsevier España, S. L. All rights reserved.

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Silva, G., Melica, B., Pires De Morais, G., Sousa, O., Bettencourt, N., Ribeiro, J., … Gama, V. (2012). Percutaneous implantation of a ventricular partitioning device for treatment of ischemic heart failure: Initial experience of a center. Revista Portuguesa de Cardiologia, 31(12), 795–801. https://doi.org/10.1016/j.repc.2012.07.007

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