Penile cancer is an uncommon primary genitourinary malignancy, the vast majority representing superficial squamous cell carcinomas. However, less common skin cancers, secondary malignancies, mesenchymal neoplasms, and hematopoietic tumors do affect the penis. Medical history, atypical presentation, and deep epicenter of a penile mass may raise question of a nonepithelial neoplasm. We describe and discuss 2 examples of rare deep-seated penile malignancies, leiomyosarcoma and B-cell lymphoma.
Thomas, K., Spiess, P., & Caracciolo, J. T. (2017). A report of two deep-seated noncutaneous penile tumors: more than meets the eye. Radiology Case Reports, 12(4), 726–730. https://doi.org/10.1016/j.radcr.2017.07.012