Resultados a largo plazo en trasplante renal de donantes con criterios expandidos

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Abstract

BACKGROUND: Kidney transplantation of expanded criteria deceased donors (DCE) has become a common clinical practice. However, DCE outcomes are inferior compared to kidney transplants from standard criteria donors (DCS).<br /><br />AIM: To evaluate intermediate and long-term outcomes of DCE transplanted patients.<br /><br />MATERIAL AND METHODS: Cadaveric kidney transplants were evaluated using a retrospective cohort of eight consecutive years. Complications and long-term function of the transplant were assessed in DCE and DCS kidney recipients.<br /><br />RESULTS: Of 213 patients analyzed, 34 (16%) underwent DCE transplantation. DCS recipients spent more time on the waiting list for transplantation (p = 0.04). DCE recipients showed higher frequency of surgical complications (p = 0.04), vascular complications (p = 0.02), acute transplant rejection (p = 0.05), and hospitalizations (p = 0.01). Creatinine (mg/dL) in DCE and DCS recipients was 2.3 and 1.5 respectively at year one (p < 0.01) and 2.6 and 1.6 respectively at year five (p < 0.01). Graft survival in the DCE group was significantly lower at 5 years (61 and 89% respectively, p < 0.01).<br /><br />CONCLUSIONS: DCE grafts are associated with lower survival, higher hospitalization rate and commonly develop surgical complications and rejections.

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APA

Valjalo, R., Reynolds, E., Herrera, P., Espinoza, Ó., & González, F. (2016). Resultados a largo plazo en trasplante renal de donantes con criterios expandidos. Revista Medica de Chile, 144(1), 22–29. https://doi.org/10.4067/S0034-98872016000100004

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