Risk factors for extended duration of acute diarrhea in young children

19Citations
Citations of this article
87Readers
Mendeley users who have this article in their library.

Abstract

Objective and Background: We sought to identify predictors of extended duration of diarrhea in young children, which contributes substantially to the near ly 1 1/2 million annual diarrheal deaths globally. Methods: We followed 6-35 month old Nepalese children enrolled in the placebo-arm of a randomized controlled trial with 391 episodes of acute diarrhea from the day they were diagnosed until cessation of the episode. Using multiple logistic regression analysis, we identified independent risk factors for having diarrhea for more than 7 days after diagnosis. Results: Infants had a 17 (95% CI 3.5, 83)-fold and toddlers (12 to 23 month olds) a 9.9 (95% CI 2.1, 47)-fold higher odds of having such illness duration compared to the older children. Not being breastfed was associated with a 9.3 (95% CI 2.4, 35.7)-fold increase in the odds for this outcome. The odds also increased with increasing stool frequency. Furthermore, having diarrhea in the monsoon season also increased the risk of prolonged illness. Conclusion: We found that high stool frequency, not being breastfed, young age and acquiring diarrhea in the rainy season were risk factors for prolonged diarrhea. In populations such as ours, breastfeeding may be the most important modifiable risk factor for extended duration of diarrhea. © 2012 Strand et al.

Cite

CITATION STYLE

APA

Strand, T. A., Sharma, P. R., Gjessing, H. K., Ulak, M., Chandyo, R. K., Adhikari, R. K., & Sommerfelt, H. (2012). Risk factors for extended duration of acute diarrhea in young children. PLoS ONE, 7(5). https://doi.org/10.1371/journal.pone.0036436

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free