Risk factors in hepatocellular carcinoma

Abstract

Hepatocellular carcinoma is the fifth most common cancer in the world. The aim of this study was to identify the possible risk factors causing HCC. Certain metabolic diseases like hepatitis B, Hepatitis C infection lead to liver cancer without causing liver cirrhosis and increases risk of HCC by 27 fold. Cirrhosis itself is an independent risk factor of inducing HCC by 5-fold. Drugs used for the treatment of diabetes have shown to cause HCC. Certain toxins like aflatoxins increase the risk of liver cancer. Anabolic steroids are known to cause HCC by mimicking the action of some hormones. Some of organic and inorganic compounds like vinyl chloride and Arsenic cause HCC. This article summarize the risk factors of Hepato Cellular Carcinoma. © 2011 Naga Anusha P.