Small non-coding RNAs, mammalian cells, and viruses: Regulatory interactions?

Abstract

Recent findings suggest that mammalian cells can use small non-coding RNAs (ncRNA) to regulate physiological viral infections. Here, we comment on several lines of evidence that support this concept. We discuss how viruses may in turn protect, suppress, evade, modulate, or adapt to the host cell's ncRNA regulatory schema. © 2007 Yeung et al; licensee BioMed Central Ltd.