The structure of human carbonic anhydrase II in complex with bromide and azide

61Citations
Citations of this article
20Readers
Mendeley users who have this article in their library.

Abstract

The three-dimensional structure of human carbonic anhydrase II complexed with azide and with bromide was investigated crystallographically. Both of these non-protonated inhibitors replace the zinc and the 'deep' water, two catalytically important water molecules in the active site of the molecule. Both the azide and the bromide ions bind in a distorted tetrahedral manner 0.4 and 1.1 Å from the zinc water position, respectively, but are in close contact (2.0 and 2.6 Å, respectively) with the zinc ion. © 1993.

Cite

CITATION STYLE

APA

Jönsson, B. M., Håkansson, K., & Liljas, A. (1993). The structure of human carbonic anhydrase II in complex with bromide and azide. FEBS Letters, 322(2), 186–190. https://doi.org/10.1016/0014-5793(93)81565-H

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free