This report describes a longitudinal case of immunocompromised patient post kidney transplant who was admitted to our institution repeatedly for treatment of various infections caused by multi-drug resistant Klebsiella pneumoniae. The patient was successfully treated with a combination of ertapenem/meropenem on multiple occasions despite the elevated MICs. Our observations corroborate previous preclinical studies and case reports showing the efficacy of double carbapenem regimens against resistant Enterobacteriaceae.
El Nekidy, W. S., Mooty, M. Y., Attallah, N., Cardona, L., Bonilla, M. F., & Ghazi, I. M. (2017). Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient. IDCases, 9, 53–55. https://doi.org/10.1016/j.idcr.2017.06.005