Transmission of the Highly Pathogenic Avian Influenza Virus H5N1 within Flocks during the 2004 Epidemic in Thailand

  • Tiensin T
  • Nielen M
  • Vernooij H
  • et al.
85Citations
Citations of this article
76Readers
Mendeley users who have this article in their library.
Get full text

Abstract

This present study is the first to quantify the transmission of avian<br />influenza virus H5N1 within flocks during the 2004 epidemic in Thailand.<br />It uses the flock-level mortality data to estimate the transmission-rate<br />parameter (beta) and the basic reproduction number (R-0). The point<br />estimates of beta varied from 2.26/ day (95% confidence interval<br />{[}CI], 2.01-2.55) for a 1-day infectious period to 0.66/ day (95% CI,<br />0.50-0.87) for a 4-day infectious period, whereas the accompanying R-0<br />varied from 2.26(95% CI, 2.01-2.55) to 2.64(95% CI, 2.02-3.47).<br />Although the point estimates of beta of backyard chickens and fighting<br />cocks raised together were lower than those of laying hens and broiler<br />chickens, this difference was not statistically significant. These<br />results will enable us to assess the control measures in simulation<br />studies. They also indicate that, for the elimination of the virus, a<br />critical proportion of the susceptible poultry population in a flock<br />(i.e., 80% of the population) needs to be vaccinated.

Cite

CITATION STYLE

APA

Tiensin, T., Nielen, M., Vernooij, H., Songserm, T., Kalpravidh, W., Chotiprasatintara, S., … Stegeman, A. (2007). Transmission of the Highly Pathogenic Avian Influenza Virus H5N1 within Flocks during the 2004 Epidemic in Thailand. The Journal of Infectious Diseases, 196(11), 1679–1684. https://doi.org/10.1086/522007

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free