One possibility for the statistical evaluation of trends in epidemiological exposure studies is the use of a trend test for data organized in a 2 × k contingency table. Commonly, the exposure data are naturally grouped or continuous exposure data are appropriately categorized. The trend test should be sensitive to any shape of the exposure-response relationship. Commonly, a global trend test only determines whether there is a trend or not. Once a trend is seen it is important to identify the likely shape of the exposure-response relationship. This paper introduces a best contrast approach and an alternative approach based on order-restricted information criteria for the model selection of a particular exposure-response relationship. For the simple change point alternative H1 : 1 =.= q
CITATION STYLE
Hothorn, L. A., Vaeth, M., & Hothorn, T. (2009). Trend tests for the evaluation of exposure-response relationships in epidemiological exposure studies. Epidemiologic Perspectives and Innovations, 6(1). https://doi.org/10.1186/1742-5573-6-1
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