Tubular organs have characteristic lumen sizes that are generated during development. Recent studies of tubular systems in Drosophila have implicated intracellular vesicle transport as an important step in lumen expansion.
Sudarsan, V. (2003, February 18). Tube morphogenesis: No pipe dream in Drosophila. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(03)00073-3