Value of microbiology study in congenital nasolacrimal duct obstruction

Citations of this article
Mendeley users who have this article in their library.


Purpose: Evaluation of the effect of different microorganisms on congenital nasolacrimal duct obstruction (CNLDO) tightness and whether probing or silastic intubation is likely to fail in a particular microorganism infection. Methods: The culture and sensitivity results of lacrimal drainage system (LDS) discharge samples from patients with CNLDO were reviewed. Different microorganisms were correlated with the severity of nasolacrimal duct (NLD) obstruction observed during surgical intervention. The success rates of probing and silastic intubation as a primary procedure for each identifiable microorganism were documented. Statistical analysis was conducted to correlate the type of microorganism with the tightness of CNLDO and treatment failure. Results: Out of 181 specimens, 22 had no growth (12.1%). LDS with positive culture had 76.6% successful probing (n= 49) and 82.1% successful silastic intubation (n= 78). Gram-positive and Gram-negative species were almost equally detected. The most prevalent organisms were Streptococcus pneumoniae and Hemophilus influenzae (48.1% and 39.2%, respectively). Tight CNLDO was more prevalent in Serratia marcescens (n= 2; 100%) and Staphylococcus aureus (n= 4; 33.3%) infections with a 7.75 Odds ratio [95% confidence interval (CI), 1.67-34.63]. Staphylococcus aureus had 37.5% successful probing; however, success was achieved in all cases with silastic intubation. Serratia marcescens infections had 100% successful silastic intubation. Conclusion: Microbiology study can predict tight CNLDO and helps in choosing the most successful treatment option. CNLDO with Staphylococcus infection and Serratia marcescens were likely to have tight NLD obstruction and silastic intubation had better outcomes. © 2012 King Saud University.




Al-Faky, Y. H., Naeem, T., Al-Sobaie, N., Al-Huthail, R., Al-Odan, H., Osman, E. A., & Mousa, A. (2012). Value of microbiology study in congenital nasolacrimal duct obstruction. Saudi Journal of Ophthalmology, 26(2), 223–228.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free