The Vascular Smooth Muscle Cell: Molecular and Biological Responses to the Extracellular Matrix

Abstract

In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also examines the proliferation and replication of SMC and its role in pharmacology and vascular disease. A must for cell, developmental, and molecular biologists, this book also will appeal to cardiologists, pathologists, and biomedical researchers interested in smooth muscle cells.Key Features* Presents a molecular, genetic, and developmental perspective of the vas smooth muscle cell* Overview sections highlight key points of chapters, including the clinical relevance of the research and expectations for future study* Appeals to both the basic biologist and to the biomedical researcher of vascular disease