Background: Darunavir has been proven efficacious for antiretroviral-experienced HIV-1-infected patients in randomized trials. However, effectiveness of darunavir-based salvage therapy is understudied in routine care in Brazil. Methods: Retrospective cohort study of HIV-1-infected patients from three public referral centers in Belo Horizonte, who received a darunavir-based therapy between 2008 and 2010, after virologic failure. Primary endpoint was the proportion of patients with viral load.
CITATION STYLE
Ribeiro, K. M., Biscione, F. M., Westin, M. R., Machado, D. P., Greco, D. B., & Tupinambás, U. (2014). Virologic and immunologic effectiveness of darunavir-based salvage therapy in HIV-1-infected adults in a Brazilian clinical practice setting: Results of a multicenter and retrospective cohort study. Brazilian Journal of Infectious Diseases, 18(1), 1–7. https://doi.org/10.1016/j.bjid.2013.04.001
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