Analysis of bile acid glucuronides in urine: group separation on a lipophilic anion exchanger

36Citations
Citations of this article
4Readers
Mendeley users who have this article in their library.
Get full text

Abstract

A Chromatographie separation of glucuronidated bile acids using the anion exchanger diethylaminohydroxypropyl Sephadex LH-20 (DEAP LH-20) is described. Group separation of non-sulfated, non-glucuronidated bile acids, bile acid glucuronides, bile acid monosulfates, and bile acid disulfates was obtained. The method allowed analysis of all these bile acid derivatives in the urine of 15 patients with cirrhosis of the liver and cholestasis. The patients excreted in mean 30.4 μmol/24h non-sulfated, non-glucuronidated bile acids, 90.3 μmol bile acid monosulfates, and 10.2 μmol bile acid glucuronides. Glycine- or taurine-conjugated were 68% of the non-sulfated, non-glucuronidated bile acids, 96% of bile acid sulfates, and 81% of bile acid glucuronides. © 1982.

Cite

CITATION STYLE

APA

Stiehl, A., Raedsch, R., Rudolph, G., Czygan, P., & Walker, S. (1982). Analysis of bile acid glucuronides in urine: group separation on a lipophilic anion exchanger. Clinica Chimica Acta, 123(3), 275–285. https://doi.org/10.1016/0009-8981(82)90172-3

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free