Asymmetric activation of extracellular signal-regulated kinase 1/2 in rat vestibular nuclei by unilateral labyrinthectomy

9Citations
Citations of this article
4Readers
Mendeley users who have this article in their library.
Get full text

Abstract

The expression of phosphorylated extracellular signal-regulated kinase 1/2 (pERK 1/2) was evaluated in the vestibular nuclei (VN) of rats following unilateral labyrinthectomy (UL). Immunohistochemistry revealed a significant asymmetrical increase in pERK 1/2 expression in the VN, 5 min after UL, after which pERK 1/2 immunoreactivity decreased rapidly and was undetectable by 90 min after UL. These results suggest that unilateral deafferentation of the vestibular system triggers intracellular signal pathways that activate ERK 1/2 in the VN. © 2004 Elsevier B.V. All rigths reserved.

Cite

CITATION STYLE

APA

Kim, M. S., Choi, M. A., Choi, D. O., Lee, M. Y., Kim, K. Y., Rhee, J. K., … Park, B. R. (2004). Asymmetric activation of extracellular signal-regulated kinase 1/2 in rat vestibular nuclei by unilateral labyrinthectomy. Brain Research, 1011(2), 238–242. https://doi.org/10.1016/j.brainres.2004.03.031

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free