Asymmetric alkylation of glycine imine esters using solid supports preloaded with base

  • Yu H
  • Takigawa S
  • Koshima H
  • 5


    Mendeley users who have this article in their library.
  • 15


    Citations of this article.


Investigations into the use of solid supports preloaded with base for the asymmetric alkylation of a benzophenone-derived glycine-imine was described. Residual traces of water on the support dramatically accelerated the reactions to complete within a few minutes. The conditions employed in the present synthesis are mild, efficient and general. Graphical Abstract. © 2004 Elsevier Ltd. All rights reserved.

Author-supplied keywords

  • Amino acids
  • Asymmetric alkylation
  • Chiral phase transfer catalysts
  • Glycine imine esters
  • Solid supports

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Haitao Yu

  • Setsuko Takigawa

  • Hideko Koshima

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free