Biosynthetic studies on flavones and C-glycosylflavones: B-ring oxidation patterns

Abstract

Data obtained by feeding 14C-labeled amino acids, a flavanone, flavones, and a C-glycosyl-flavone to axenically cultured Spirodela polyrhiza indicated that: the B-ring oxidation pattern of flavone-O-glycosides was determined at the flavone level of biosynthesis and was essentially irreversible; that the B-ring oxidation pattern of C-glycosylflavones was determined prior to C-glycosylation, probably at the flavanone stage; and that flavones and C-glycosylflavones were not static end products of metabolism but undergo turnover. Specific activities were determined for the in vivo incorporation of each of the above kinds of compounds into flavone C- and O-glycosides of S. polyrhiza. © 1975.