Chiral [2.2]paracyclophanes - III. The preparation of unique homochiral amino-acids derived from [2.2]paracyclophane

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Abstract

The synthesis and characterisation are described of homochiral (+)-4- carboxy-13-amino-[2.2]paracyclophane and (+)-4-carboxy-12-amino- [2.2]paracyclophane, which are unique, linearly chiral amino-acids which may act as β-turn mimics.

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Pelter, A., Crump, R. A. N. C., & Kidwell, H. (1997). Chiral [2.2]paracyclophanes - III. The preparation of unique homochiral amino-acids derived from [2.2]paracyclophane. Tetrahedron Asymmetry, 8(23), 3873–3880. https://doi.org/10.1016/S0957-4166(97)00590-9

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