Cloning of a polymorphic DNA fragment from the genome of Leishmania donovani

  • Ellis J
  • Knapp T
  • Crampton J
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Abstract

Recombinant DNA clones, containing highly repetitive DNA sequences, have been isolated from a Leishmania donovani genomic DNA library prepared in the replacement vector λgt·WES·λB. Two clones, probably telomeric in location, have been characterised and show a restriction fragment size polymorphism. Evidence is presented which suggests that L. donovani is diploid for this cloned genomic locus. © 1989.

Author-supplied keywords

  • Leishmania
  • Ploidy
  • Polymorphism
  • Repetitive sequence
  • Telomeres

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Authors

  • John Ellis

  • Teresa Knapp

  • Julian Crampton

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