Abstract
A new synthesis of enantiomerically highly enriched N-substituted furoylalanines has been developed. This process involves the combination of crystallisation induced asymmetric transformation (CIAT) and a conjugate addition of N-nucleophiles to furoylacrylic acids. Further transformations to furoylalanines and substituted furylcarbinols are also described. © 2006 Elsevier Ltd. All rights reserved.
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CITATION STYLE
Jakubec, P., Berkeš, D., Šiška, R., Gardianová, M., & Považanec, F. (2006). Crystallisation induced asymmetric transformation (CIAT) in the synthesis of furoylalanines and furylcarbinols. Tetrahedron Asymmetry, 17(11), 1629–1637. https://doi.org/10.1016/j.tetasy.2006.04.024
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