Effects of nitrous oxide exposure on Met-enkephalin levels in discrete areas of rat brain

Abstract

Rat were exposed to 80% nitrous oxide in oxygen for 1 and 18 h. Met-enkephalin levels in the dorsal raphé, medial thalamus, periaqueductal grey, raphé magnus and locus coeruleus were measured by radioimmunoassay in control and treated animals. There was no change in Met-enkephalin levels at either time point in any of the brain areas examined. © 1984.