Thioamides undergo oxidative dimerization on treatment with hypervalent iodine(V)-containing reagents, particularly o-iodoxybenzoic acid (IBX), in the presence of tetraethylammonium bromide (TEAB) to generate 3,5-disubstituted 1,2,4-thiadiazoles in excellent yield. © 2009 Elsevier Ltd. All rights reserved.
Patil, P. C., Bhalerao, D. S., Dangate, P. S., & Akamanchi, K. G. (2009). IBX/TEAB-mediated oxidative dimerization of thioamides: synthesis of 3,5-disubstituted 1,2,4-thiadiazoles. Tetrahedron Letters, 50(42), 5820–5822. https://doi.org/10.1016/j.tetlet.2009.07.155