The effect of isatin (indole-2,3-dione) on d-glucose uptake in rat intestine was studied. Isatin at 1-6 mm concentrations appreciably depressed sodium-dependent glucose uptake, but had no effect on sodium-independent sugar uptake in intestine. Kinetic studies revealed isatin to be a noncompetitive inhibitor of sugar uptake. The inhibitory constant (Ki) was of the order of 7.80 mm. © 1983.
CITATION STYLE
Nagpal, J. P., Wali, R. K., & Mahmood, A. (1983). Isatin: An inhibitor of sodium-dependent d-glucose uptake in rat intestine. Biochemical Medicine, 29(1), 46–50. https://doi.org/10.1016/0006-2944(83)90052-2
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