Lordosis behavior and GABAergic neurotransmission

  • Fernández-Guasti A
  • Larsson K
  • Beyer C
  • 4


    Mendeley users who have this article in their library.
  • 22


    Citations of this article.


γ-Aminobutyric acid (GABA) (1.0 μg/cannula) or muscimol (50 ng/cannula) was injected into the ventromedial hypothalamus or the lateral septi nuclei of ovariectomized rats brought to sexual receptivity by combined treatment of estrogen and progesterone. Inhibitory effects of GABA or muscimol were observed on the lordosis behavior. Futthermore, systemic (1.0 mg/kg) or intrahypothalamic (50 ng/cannula) picrotoxin administration was followed by a statistically significant increase in lordosis behavior in ovariectomized, estrogen-primed rats. No such effect was observed in ovariectomized-adrenalectomized animals, indicating its dependence on adrenal secretions. Present results do not support the hypothesis of a GABAergic mechanism in the control of lordosis behavior. © 1986.

Author-supplied keywords

  • GABA
  • Lateral septi nuclei
  • Lordosis behavior
  • Muscimol
  • Picrotoxin
  • Ventromedial hypothalamus

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • A. Fernández-Guasti

  • K. Larsson

  • C. Beyer

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free